Metabolic Daily

ongoing support
Candida & Yeast Balance
Gut & Digestive Health
Immune Defense
Maintenance & Recovery
Probiotics & Prebiotics
A next-generation probiotic with live Akkermansia muciniphila plus four butyrate-producing strains. Supports gut barrier health, healthy metabolism, and balanced appetite in one daily capsule.
Pros
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Live Akkermansia plus four butyrate-producing strains
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Shelf stable, no refrigeration required
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Third-party tested with cGMP certified manufacturing
Cons
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Mild bloating or gas is common in the first weeks
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Consult a physician first if pregnant, nursing, or on prescriptions
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Full metabolic benefits may take about 90 days of daily use
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From

$49.00

10% off all supplements
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MARTYROSS10
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From

$49.00

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TreatLyme and Dr. Marty Ross, MD, are affiliated with Femologist. We may earn a commission on purchases made through this link or code.
Pros
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Live Akkermansia plus four butyrate-producing strains
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Shelf stable, no refrigeration required
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Third-party tested with cGMP certified manufacturing
Cons
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Mild bloating or gas is common in the first weeks
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Consult a physician first if pregnant, nursing, or on prescriptions
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Full metabolic benefits may take about 90 days of daily use
Quick Facts
Key Ingredients
Probiotic Blend 300 million AFU
Third-party Testing
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cGMP
Dietary
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Gluten-free
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Non-GMO
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Written by
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Dr. Marty Ross, MD
Updated
September 24, 2026
On This Page
Dr. Ross's Take
How Dr. Ross Uses It
The Research
References
Manufacturer's Description
Common Questions
Reviews

Dr. Ross's Expert Review

Metabolic Daily is a different kind of probiotic. Most products on the shelf carry Lactobacillus and Bifidobacterium. This one carries next-generation strains: live Akkermansia muciniphila plus Clostridium butyricum, Clostridium beijerinckii, Bifidobacterium infantis, and Anaerobutyricum hallii, which are known as butyrate producers.

Akkermansia lives in the mucus layer that protects the intestinal lining. It supports the mucin barrier and the gut lining itself. The other strains produce butyrate, a short-chain fatty acid that gut cells use for fuel, and they help maintain a healthy intestinal environment. The research behind Akkermansia has grown fast, and the human trials on butyrate producers are encouraging, though much of this science is still young.

In my practice, I reach for this type of product when someone is working on gut barrier health or metabolic support. The strains support healthy sugar and fat metabolism and help the body maintain balanced appetite signals. It is shelf stable, so no refrigeration is needed, which makes daily use easier.

In the first one to three weeks, mild digestive changes like bloating or gas are common as the gut adjusts. That is not a reason to quit, but keep your physician informed. Give it time: the maker suggests up to 90 days for the fuller metabolic benefits, which matches how slowly the gut microbiome shifts.

This is a supplement, not a replacement for the foundations: a fiber-rich diet, sleep, movement, and treating the infections and inflammation underneath. Work with your physician on where it fits in your plan.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Dr. Ross has a financial relationship with the Femologist store, where this product is sold.

How I Use It in My Practice

In my practice, I use Metabolic Daily as a daily ongoing probiotic for people rebuilding gut barrier health or metabolic balance. The manufacturer suggests 1 capsule daily with food. I tell people upfront to expect mild bloating or gas in the first one to three weeks as the gut adjusts, and to ride it out unless it worsens. I give it a full 90 days before judging results, because microbiome changes are slow. It is shelf stable, and refrigeration after opening is optional. If someone is pregnant, nursing, or on prescription medication, their physician should review it first.

This reflects Dr. Ross's clinical experience and is educational, not medical advice. Work with your treating physician before starting, stopping, or changing any supplement or medication.

The Research, in Dr. Ross's Words

The evidence for the butyrate-producing strains in this product is early but consistent. A 2025 study found that Clostridium butyricum TO-A efficiently produces butyrate from lactate and acetate, supporting its role as a probiotic for gut health. A 2025 study found that supplementing human fecal microbiomes with Anaerobutyricum hallii increased butyrate production over time, especially in microbiomes that started with low abundance, and a 2023 review discusses A. hallii and related species as next-generation beneficial microbes with promise for metabolic health.

The strongest human signal comes from a 2019 proof-of-concept trial in overweight adults: supplementing with live Akkermansia muciniphila was safe, well tolerated, and improved several metabolic markers. And a review article from Nature Reviews in 2022 lays out the evidence for support of the intestinal mucin barrier and gut lining by Akkermansia. The strain-specific lab work on the butyrate producers adds lab support for a mechanism of action, but the human proof rests on the Akkermansia arm.

The limits are real. These are strain-specific studies, several are recent, and none tests this exact five-strain blend as a whole against metabolic outcomes in a controlled trial. The Akkermansia muciniphila literature is large and growing but much of it is mechanistic. The laboratory research base is promising, the research proof in people is growing.

References
From:
Pendulum
The right strains for metabolic health. Metabolic Daily is formulated with the most beneficial bacterial strains. Akkermansia muciniphila: An essential bacteria strain that strengthens the all-important gut barrier and produces postbiotics for digestive and metabolic health.
Directions of Use
Adults take 1 capsule daily with food.
Does not contain
If you are pregnant, nursing, or taking any medications, please seek the advice of a healthcare provider prior to use.
Excerpted from Pendulum's product information. These statements have not been evaluated by the Food and Drug Administration.
Supplement Facts
Serving Size: 1 Capsule
Servings Per Container: 30
Amount Per ServingAmount% DV
Probiotic Blend
Clostridium butyricum WB-STR-0006, Clostridium beijerinckii WB-STR-0005, Bifidobacterium infantis, Anaerobutyricum hallii WB-STR-0008, Akkermansia muciniphila WB-STR-0001
300 million AFU
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    Purple bottle of Pendulum Metabolic Daily capsules with Akkermansia mucinphila

    Common Questions about Metabolic Daily

    Answers are general educational information, not medical advice for your situation.
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    Metabolic Daily
    By Pendulum
    From $49.00 · Save 10% with code MARTYROSS10

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