CoreBiotic Sensitive is the probiotic I reach for when a regular probiotic causes intestinal discomfort. Some people bloat or react to the prebiotic fibers most formulas include. Researched Nutritionals formulated this probiotic without any prebiotic fiber, which also makes it a fit for anyone following a low FODMAP diet. It is the same 11 billion CFU, three-strain formula as their original CoreBiotic, minus the fiber.

The three strains here, Bacillus coagulans and Bacillus subtilis, are spore-forming soil-based organisms. The spore shell survives stomach acid, which kills many standard probiotic strains before they reach the intestines. Spore forming probiotics do not require refrigeration. Once in the gut, the bacteria leave the spore form and get to work through competitive exclusion, crowding out organisms you do not want.

In my practice, I use it for people managing gut sensitivity or following a low FODMAP approach. Spore forming probiotics support healthy digestion, gut-associated immune function, and the intestinal barrier. A healthy diet is also critical.

Each strain here has human trial data behind it, including trials on abdominal comfort, bloating, motility, and stool consistency. Probiotic research is strain-specific, so I pay attention to which strain a study tested. The strains in this product are fully sequenced and registered, so you get the same organisms every bottle.

I suggest two capsules once a day, at least 30 minutes before eating. One caution: the medium chain triglycerides in this product come from coconut, so anyone with a tree nut allergy should review the label with their physician. Pregnancy and nursing call for a physician’s review too.

For sensitive guts, this is one of the cleanest probiotic options I use. No fiber, no refrigeration, well-researched strains, and a simple once-daily dose.