Quick Facts

Dr. Marty Ross, MD
Dr. Ross's Expert Review
Creatine is an amino acid the body makes and uses to reload energy quickly inside cells. Most people know it for muscle, and that works. What interests me more in the people I see is the brain. The brain burns a large share of the body’s energy, and in chronic illness the energy factories inside cells run low. Creatine gives those cells a quick-reload energy buffer.
The research backs the brain angle better than for most supplements I discuss: a controlled trial showed improved brain performance in vegetarians, meta-analyses of creatine and memory report benefits in healthy adults, and a 2025 pilot study looked at creatine in Alzheimer’s. For people with brain fog and low cognitive stamina in my practice, it is one of the simple supports I reach for.
This Thorne product is micronized creatine monohydrate, 5 grams per scoop, 90 servings per container. It is made without gluten, dairy, or soy, and it holds NSF Certified for Sport, which means an independent program has verified what is in the tub.
Work with your physician on where it fits in a full regimen.
How I Use It in My Practice
I use creatine as ongoing daily support for brain energy, and for muscle when someone is rebuilding strength. My usual approach is 1 scoop (5 grams) a day in at least 8 ounces of water or juice. It works by saturation, not timing, so I tell people to pick a time they will not skip and keep it consistent. When someone wants more cognitive support I move to 2 scoops a day for a while and watch how they feel. Unlike the enzymes I use, there is no empty-stomach rule here: it mixes fine with food or a smoothie.
The Research, in Dr. Ross's Words
The research record on creatine and the brain is stronger than for most supplements I discuss. The 2003 double-blind cross-over trial showed oral creatine monohydrate improved brain performance in vegetarians, the population most likely to run low. A 2023 meta-analysis of randomized controlled trials on memory in healthy individuals reported benefits, and a 2024 systematic review and meta-analysis on cognitive function in adults added more pooled data. In 2025 a pilot study in Alzheimer’s looked at feasibility, brain creatine levels, and cognition, which tells me researchers treat this as a serious brain-energy question.
The muscle side is older and settled: creatine monohydrate at 5 grams a day supports the quick energy reload inside muscle cells. The NSF Certified for Sport mark on this product matters here because an independent program tested it for banned substances and verified the label claim.
What I do not have is research on creatine in tick-borne illness specifically. I use it for the brain energy problem I see in practice, and I watch what changes for the person in front of me.
References
Supplement Facts
| One Scoop (5 g) Contains:|% DV | Amount | |
|---|---|---|
Creatine Monohydrate | 5 g | |
*Daily Value (DV) not established. | ||







