Quick Facts

Dr. Marty Ross, MD
Dr. Ross's Expert Review
CoQ10 Power is one of the simplest, highest-value supports I use for energy. Coenzyme Q10 is the molecule mitochondria use to turn food into ATP, the energy currency of the cell. Tissues with the highest energy demand, the heart, the brain and nerves, the immune system, rely on it heavily. The body makes its own CoQ10, but production falls with age and with certain medications, and low levels are one reason fatigue shows up in the people I see.
In my practice, CoQ10 Power fits into two kinds of plans. First, mitochondrial support for anyone with stubborn fatigue, where it works alongside other mitochondrial nutrients rather than alone. Second, cardiovascular support, since the heart’s energy demand is constant.
Each softgel carries 400 mg of pure, naturally fermented ubiquinone, the traditional and most-studied form of CoQ10. The softgel uses GMO-free sunflower oil and sunflower lecithin to carry the fat-soluble nutrient into the body, and there is no titanium dioxide in the casing.
CoQ10 has one of the deeper research files among supplements. Reviews covering dozens of trials describe its role in cellular energy and its antioxidant activity, and clinical work in cardiovascular medicine has tested it directly in people. Be aware the results vary by population and dose, and much of the strongest work sits in cardiology literature rather than in chronic illness literature.
I suggest one to three softgels a day, with or without food, to cover most situations. One caution is firm: this should not be used by anyone taking atovaquone, found in Mepron and Malarone. Pregnancy and nursing call for a physician’s review first.
This is a clean, well-absorbed, therapeutic-strength CoQ10 at a dose that makes one or two softgels a day practical. For energy and heart support, it earns its spot in my protocols.
How I Use It in My Practice
I use CoQ10 Power mostly as ongoing mitochondrial and cardiovascular support. Most people in my practice do well on one or two softgels a day; I move toward three when fatigue is more stubborn, always with the rest of the regimen in mind. Because it is fat-soluble, taking it with a meal that has some fat helps absorption, though the sunflower oil base does some of that work. It may take months to see benefit. Anyone taking atovaquone, found in Mepron and Malarone, should not take this product, and I confirm prescriptions at every visit. Pregnancy and nursing call for a physician’s review first.
The Research, in Dr. Ross's Words
CoQ10 has one of the deeper research databases among support supplements. CoQ10 sits inside the mitochondrial membrane, where it carries electrons between the protein complexes that build ATP, and it doubles as a lipid antioxidant. Reviews from 2018 and 2021 lay out these bioenergetic and antioxidant mechanisms as the basis for everything the nutrient does.
The clinical side is where the research base gets interesting. A 2025 review covering cardiovascular medicine points to the Q-SYMBIO trial, which reported improvements in functional capacity and ejection fraction in heart failure patients taking CoQ10. A 2020 review of clinical evidence reaches similar conclusions about hemodynamic parameters. I read those as strong signals in a specific, medically supervised population.
One comparison matters for buyers. A 2024 review of 28 trials found both ubiquinone and ubiquinol support cardiovascular function, while the longer-term outcome differences in the literature were observed with ubiquinone, the traditional form this product uses.
In my read of this research, the mechanism is solid, the cardiology trials are encouraging, while the evidence in chronic fatigue and everyday energy is thinner. I use it to support energy and heart health
References
Supplement Facts
| Amount Per Serving | Amount | |
|---|---|---|
Calories | 9 | |
Total Fat | 0.8 g | |
Coenzyme Q-10 | 400 mg | |







