CytoQuel

ongoing support
Energy & Fatigue
Herx & Cytokine Support
Nervous System & Stress
Pain Support
A five-ingredient cytokine formula from Researched Nutritionals combining black tea extract, NAC, CurcuWIN turmeric, annatto tocotrienols, and trans-resveratrol to support healthy cytokine balance and a balanced inflammatory response.
Pros
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Best for ongoing cytokine balance support during regimens that stir up cytokine excess.
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Where it fits: die-off support in a sensitive patient protocol.
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Best as a once-daily formula when inflammation stays turned up.
Cons
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Watch for: 12 mg of caffeine per serving from black tea extract.
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Sensitive patients may need to start with one capsule a day.
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Keep apart from vitamin E products; tocopherols compete with tocotrienols.
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$64.98

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From

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Pros
Image
Best for ongoing cytokine balance support during regimens that stir up cytokine excess.
Image
Where it fits: die-off support in a sensitive patient protocol.
Image
Best as a once-daily formula when inflammation stays turned up.
Cons
Image
Watch for: 12 mg of caffeine per serving from black tea extract.
Image
Sensitive patients may need to start with one capsule a day.
Image
Keep apart from vitamin E products; tocopherols compete with tocotrienols.
Quick Facts
Key Ingredients
CQ Blend 1850 mg
Third-party Testing
Dietary
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GMO-free
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Soy-free
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Vegan
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Written by
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Dr. Marty Ross, MD
Updated
September 24, 2026
On This Page
Dr. Ross's Take
How Dr. Ross Uses It
The Research
References
Manufacturer's Description
Common Questions
Reviews

Dr. Ross's Expert Review

CytoQuel is one of the tools I reach for when cytokines are driving symptoms and illness. Cytokines are immune messengers. A healthy immune system turns pro-inflammatory cytokines on to face a threat, then turns them back down when the work is done. In many of the people I see, the cytokine off switch does not work, and inflammation stays turned up long after it has served a purpose.

The formula combines five ingredients to balance cytokines: black tea extract standardized to EGCG, N-acetyl cysteine, CurcuWIN turmeric extract, DeltaGold tocotrienols, and natural trans-resveratrol. Each supports healthy cytokine balance through its own mechanism. The turmeric here is worth a comment. Plain curcumin absorbs poorly. CurcuWIN absorbs far better, and a form that actually gets in is the one that can do its job.

The formula itself was tested in an 8-week human study published in the Journal of Pain Research, which is more testing than most combinations get. That study comes from the maker, so I hold it as a promising start, not the final word. The individual ingredients each have human research behind them.

In my practice, CytoQuel fits best as ongoing support during regimens that stir up cytokine excess that can hurt the immune system, and when comfort and sleep pay the price for cytokines that will not quiet down. It is not a germ killer, and I do not use it as one. It is a balancing tool, and a well-built one.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Dr. Ross has a financial relationship with the Femologist store, where this product is sold.

How I Use It in My Practice

I most often use CytoQuel for people when inflammation stays turned up. The dose I use is three capsules once a day with a meal. Sensitive patients do better starting at one capsule a day with food for the first week, then three capsules in week two and beyond. I keep it away from vitamin E products, since tocopherols can compete with the tocotrienols. The black tea extract adds 12 mg of caffeine per serving, so in caffeine-sensitive people I place the dose earlier in the day. Each bottle holds 90 capsules, a one-month supply at the full dose. For pregnant or nursing patients, this one belongs with your physician.

This reflects Dr. Ross's clinical experience and is educational, not medical advice. Work with your treating physician before starting, stopping, or changing any supplement or medication.

The Research, in Dr. Ross's Words

My research review shows the strongest thing CytoQuel has going for it is its own human trial. The maker’s study, published in the Journal of Pain Research, was an 8-week trial in people and reported support for healthy cytokine function, vascular health, and sleep quality. Manufacturer funded research has its drawbacks, but the trial is a start and suggests benefits.

The ingredient science is a mix. A 2024 review of black tea clinical trials found lower CRP and shifts in immune cell populations, pointing to vascular health support. Curcumin reviews from 2017 and 2021 describe antioxidant activity and NF-kB-related effects on inflammation, though much of that mechanism work is preclinical. A 2015 systematic review found NAC safe and well tolerated across trials in neurology and psychiatry, which is reassuring for daily use. The 2016 tocotrienols review and the 2020 resveratrol randomized trial each show circulatory and protective effects in humans.

What these papers do not do is prove that this blend treats any specific condition. They support a structure-and-function case that could work in humans: these ingredients support healthy cytokine balance. The specific absorption forms here, CurcuWIN and DeltaGold, are not the ones most of the studies used.

References
From:
Researched Nutritionals
Backed by a peer-reviewed clinical study published in the Journal of Pain Research, CytoQuel® is a comprehensive formula developed to support healthy cytokine function. Features: Published, peer-reviewed clinical research. GMO-Free, Vegan, Soy Free. CurcuWIN™ turmeric extract (46x more absorbable than standard curcumin). DeltaGold® tocotrienols (annatto derived pure delta & gamma tocotrienols). Also contains EGCG, NAC, and natural Trans-Resveratrol (from Japanese knotweed, Polygonum cuspidatum extract). Mechanisms of Action: Supports healthy, balanced cytokine function. Promotes healthy MMP-9 levels.
Directions of Use
Take 3 capsules once per day with a meal, or use as directed by your healthcare professional.
Does not contain
corn
crustacean-shellfish
eggs
fish
gluten
milk
peanuts
soy
tree-nuts
wheat
Caution: If pregnant or nursing, consult your health care professional before use. Proposition 65 Warning for California Consumers: This product contains herbs and / or minerals which come from the soil. As such, it may contain small amounts of naturally occurring chemicals. CA WARNING: Can expose you to lead, a reproductive toxicant. See www.P65Warnings.ca.gov/food
Excerpted from Researched Nutritionals's product information. These statements have not been evaluated by the Food and Drug Administration.
Supplement Facts
Serving Size: 3 Capsules
Servings Per Container: 30
Amount Per ServingAmount% DV
CQ Blend
Black Tea Extract (50% EGCG), N-Acetyl Cysteine, CurcuWIN Turmeric Extract, DeltaGold Tocotrienols, Resveratrol (Natural Trans-Resveratrol)
1850 mg
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    CytoQuel dietary supplement bottle, 90 capsules, with "Healthy Cytokine Support" label.

    Common Questions about CytoQuel

    Answers are general educational information, not medical advice for your situation.
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    CytoQuel
    By Researched Nutritionals
    From $64.98 · Save 10% with code MARTYROSS10

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