Quick Facts

Dr. Marty Ross, MD
Dr. Ross's Expert Review
Isatis is one of the workhorse herbs of traditional Chinese medicine, and it earns its place in modern herbal immune-support regimens. The Montana Farmacy version is a straightforward traditional preparation: Isatis indigotica root and leaf, extracted at a 1:5 ratio in organic cane alcohol, handcrafted in small batches.
I use Isatis inside immune-supporting herbal plans, most often following the Buhner-style approach where it sits alongside other immune-supporting herbs. Where some herbs in those plans lean toward one germ or one system, Isatis covers broad ground, with lab research behind antiviral mechanisms of its compounds, and a long traditional record of use in fever and inflammatory conditions.
Dosing is simple: one dropper, one to three times a day. People new to herbal regimens sometimes start lower and build up, which is reasonable with any herb in these plans, since some people report temporary symptom changes when starting herbal plans.
A few practical points. The label says avoid it during pregnancy which I agree with. And Isatis is part of a whole management plan, rather than a single herbal support. Discuss adding the herb with your physician.
The honest evidence picture: the antiviral and anti-inflammatory findings for Isatis indigotica are based on laboratory work plus a collective history of traditional use. There are no human trials of this tincture. I use it because the mechanism of action based on lab research, the traditional use, and clinical experience all point positively in the same direction.
How I Use It in My Practice
I use Isatis as one of the herbs in short-course immune-supporting herbal plans, most often in Buhner-style plans. The dose I work with is one dropper one to three times a day, and I have sensitive patients start at the low end and build up the dose. Work with your physician to decide how long to stay on it as part of a full support plan.
The Research, in Dr. Ross's Words
The research on Isatis indigotica is preclinical laboratory work. Clemastanin B, a lignan from the root, showed broad anti-influenza activity in vitro against human and avian influenza A and B viruses. The extract and its indirubin constituent inhibited Japanese encephalitis virus in cell studies. Root compounds inhibited the SARS coronavirus 3C-like protease in vitro, and animal studies of the root support its traditional antinociceptive, anti-inflammatory, and fever-response use.
The evidence does not include human trials of Isatis in any tick borne illness, in chronic viral illness, or of this 1:5 tincture at all. The lab findings establish mechanisms of action, and the traditional use record is deep. I recommend this herbal medicine based on the traditional use track-record and my clinical observations.
References
Supplement Facts
| Amount Per Serving | Amount | |
|---|---|---|
Isatis (Isatis indigotica) | 554 mg | |





