How to Manage Extreme Sensitivity in Lyme Disease or Mold Toxicity

Extreme Sensitivity to Medicines & Supplements — Key Factors

In this video article Marty Ross MD outlines the key steps to manage extreme medicine and supplement sensitivity in tick-borne diseases like Lyme disease or mold toxicity. Dr. Ross discusses the role and management of

mast cell activation syndrome,
intestinal yeast overgrowth,
limbic system training, and
Bartonella infection.

Key Interventions Mentioned

Mast Cell Stabilizers

Thorne Quercetin Phytosome 250 mg — work slowly up to 2 pills three times a day.
Integrative Peptides KPV — work slowly up to 1 pill 2 times a day.
Zyrtec 10 mg 1 pill 1 time a day (this is a pharmaceutical found over-the-counter at pharmacies)

Intestinal Yeast Overgrowth

Elim-A-Cand by Researched Nutritionals — work slowly up to 40 drops two times a day if you can.

Limbic System Training

Dig Deeper

For more information about the ideas discussed in this video see the following articles found at Treat Lyme by Marty Ross MD.

Video Transcript

Below is an edited video transcript of this article.

Let’s see. My fifteen year old daughter has been very sick for three years, extreme fogginess, feels like she’s in a dream, can’t think clearly, among many other symptoms. Last year, we learned of mold toxicity via RealTime lab tests. This summer, she was diagnosed with Bartonella via MDL and Western Blot.

She’s extremely, extremely sensitive binders and treatments, so we have been at a standstill. She is on KPV peptide and minerals and B2, trinistatin and therbiotic Candida complex, and her symptoms flare terribly. How do you treat when somebody is so sensitive? We’ve tried microdosing everything.

Could candida still be a big factor? GI map shows very high candida last year.

All right. So without getting into the specifics of your daughter, there’s a few things, principles that I can talk about, all right?

So, when somebody has a lot of sensitivity, there’s two, three things initially in a treatment that I like to focus on. Maybe four things but number one, there usually is a component of what is known as mast cell activation syndrome which is your mast cells, which are the allergy cells in the body become reactive and release histamines and cytokines against everything. Okay? So one of the principles we like to do is do things to stabilize the mast cells.

The KPV peptide is one thing that can do that. Another thing that can do that also is quercetin.

Quercetin is a bioflavonoid that is found in onions and other and in the skin of color for fruits and vegetables, and it helps stabilize your mast cells so they’re not as reactive and releasing their histamines. A second thing that we’ll also do usually is get people on an antihistamine like Zyrtec to block the histamine receptor. So the two essential steps in mast cell activation is stabilize your mast cells with a mast cell stabilizer like a quercetin and then use some H1 blockers, histamine blockers, like Zyrtec or Claritin can sometimes be helpful there too, okay?

Second thing to consider when you have mast cell activation is what in the intestines could be really turning on those mast cells that line the intestinal tract, although mast cells are found everywhere. But keep in mind, sixty to seventy percent of the mast cells in the body are found in your intestinal tract, or I should actually say sixty to seventy percent of the immune cells in the body line the intestinal tract, all right? And if you have too many yeast in the intestines, that’s gonna trigger allergic reaction within the mast cells, which is gonna make them further trigger happy to release their stuff to any stimulus.

So, yes, I also like to look at yeast, and if it’s there as part of decreasing sensitivity, stabilizing mast cells, I like to focus on that too. Okay, number three, when somebody has this kind of reactivity, we also wonder about whether their limbic system has been too turned on. So the limbic system is part of your brain that’s in charge of your flight or fight response, your reproduction. It gives us the drive as to whether we’re going to eat.

And if it’s too trigger happy, you get all these adrenaline rushes as well too.

In people with chronic tick borne infections that are either early in their treatment that have been very sick for a while, the limbic system can get stuck on, or if somebody’s even knocked down a lot their germ load and they’re still not fully recovering, we sometimes think that the limbic system is too turned on too and so there’s some things we can do about that, right? So, one of the foundation things that you can do is retrain the limbic system And there’s a number of programs out there that do that. But essentially, they’re you’re learning to do things to calm triggers that stimulate you. So you can do things like meditation, you learn breathing exercises, You learn ways of reframing the things that scare you so that you’re just kind of gradually tuning that part down. Okay. So programs that do that kind of thing.

One is a program called Primal Trust. That’s P R I M A L. That’s one, okay? There’s another method called the Gupta method which tends to be more meditative if you will and then, there is another one program designed by somebody named Annie Hopper called the Dynamic Neuro Retraining System or DNRS. And so all three of those may give a person benefit, alright?

So you may wanna just read online, Google those, and see which one resonates with you. Each program can work. Each program is not necessarily for you, okay? So, for instance, the Annie Hopper program, I think is very beneficial but it’s more boot camp like.

It’s very regimented, okay?

Gupta tends to be more meditation oriented. Primal trust, I’ve heard a lot of people have used that. They find it kind of to be an in between program that works pretty well, alright? So, you need to kinda calm down that agitated part of the nervous system called the limbic system that’s causing an over release of your adrenaline systems and overactivity there and just react to this.

You need to calm that down. Secondly, as best as you can, you need to stabilize the mast cells. Okay. Alright.

And part of that is getting yeast under control. And then number four, often, often when you have this kind of sensitivity, Bartonella is part of it. It’s just been something I’ve learned over time. Okay.

So how would I how do I approach somebody in this situation?

I first of all start by getting them into a Gupta Primal Trust or a DNRS. Okay? I just start there. And I try to see if at a first visit, if I can at least get them to start a quercetin and maybe a KPV and maybe a Zyrtec, all right?

And I will have them start one thing at a time. So I might have them just start by taking a half a capsule of quercetin, trying to work up to a total of five hundred milligrams twice a day. Quercetin comes as a two fifty milligram capsule, at least the brand I like to use. I like using a brand, a product made by Thorne called Quercetin Phytosome.

And if you can just get on any amount that you can tolerate and gradually try to work that up, okay? Try to see if you can at least get up to two fifty milligrams twice a day. Once a person has done that, then I might add in a KPV.

You’ve gotta be careful with the KPV, though, although it does sound like it would be a good thing. KPV also has some antimicrobial properties. And so it could be killing germs, triggering increased herx reactions, or cytokines that has a person feeling well or worse. So, I wouldn’t start with a KPV.

I would get them on a quercetin first then I might come back and add in a KPV. Okay. So, once I’ve got them doing the limbic system retraining and I’ve got them on maybe one or two things to help with stabilizing their muscle activation syndrome, then and only then might I start working on things to kill a yeast in the intestines. Alright?

And I would start very small. This is one situation where I would tend to use a substance that is a liquid anti yeast medication because you can microdose. All right. So for instance, I might look at using a product by Research Nutritionals, which is called Elim-A-Cand, and that’s E L M I A canned, C A N D.

And normally, when you’re on full dosing of a Elim-A-Cand, you would wanna do forty drops twice a day, but I would never, never, never, never start a sensitive person there. I might start a sensitive person on half a drop once a day.

Half a drop. Alright. So how do you do half a drop? Well, you put a drop in an ounce of water and you drink half an ounce.

That’s half a drop. Okay. But you start very, very slow and you work up as tolerated. Okay.

So those are just some of the general principles. Getting through. This can really be a difficult situation. I have to admit, but you can, you can, especially if you throw in the limbic system retraining and you do some good work trying to stabilize your mast cells to begin with.

Okay. All right.

Boy, I wish your fifteen year old well. All right.

Thanks for the question.

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